GONZALEZ LAB PUBLISHED WORK

Associate Professor Publications 2021-present
 

2024

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74.  Yao Y, Thibault AMlle , Zhang B, Lucero B, Perez-Tremble R, Lucero B, McGrosso D, Gonzalez DJ, M.-Y. Lee V, Ballatore C, and Brunden KR. A Small Molecule Microtubule Stabilizing Agent Safely Reduces Aβ Plaque and Tau Pathology in Transgenic Mouse Models of Alzheimer’s Disease. Alzheimer's & Dementia: The Journal of the Alzheimer's Association (accepted April 2024)

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73. Gonzalez CG, Stevens TW, D'Haens G, Gonzalez DJ, Dulai PS. Crohn’s Patient Serum Proteomics Reveals Response Signature for Infliximab but not Vedolizumab. Inflammatory Bowel Diseases (accepted Jan 2024).

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2023

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72. Buzun E, Hsu CY, Sejane K, Oles RE, Ayala AV, Loomis LR, Zhao J, Rossitto LA, McGrosso G, Gonzalez DJ, Bode L, Chu H. A bacterial sialidase mediates early life colonization by a pioneering gut commensal. Cell Host & Microbe (accepted Nov 2023).

 

71. Zuniga-Hertz JP, Chitteti R, Dispenza J, Cuomo R, Bonds JA, Kopp EL, Simpson S, Okerblom J, Maurya S, Rana BK, Miyonahara A, Niesman IR, Maree J, Belza G, Hamilton HD, Stanton C, Gonzalez DJ, Poirier MA, Moeller-Bertram T, Patel H. Meditation-induced bloodborne factors as an adjuvant treatment to COVID-19 disease. Brain, Behavior, & Immunity - Health (accepted Aug. 2023)

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70. Gu L, Zhu Y, Watari K, Lee M, Liu J, Perez S, Thai M, Mayfield J, Zhang B, Cunha e Rocha K, Li F, Kim L, Jones AC, Wierzbicki IH, Liu X, Newton AC, Kisseleva T, Lee JH, Ying W, Gonzalez DJ, Saltiel A, Simon M, Karin M. Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness. Cell Metabolism (accepted March 2023).

2022

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69. Sauceda C, Bayne C, Sudqi K, Gonzalez A, Dulai PS, Knight R, Gonzalez DJ, Gonzalez C. Stool Multi-omics for the Study of Host-Microbe Interactions in Inflammatory Bowel Disease. Gut Microbes. (accepted Nov 2022).

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68. Hayat O, Ullah N, Sirajuddin M, Giardini MA, Nguyen JV,. Francisco KR,. Liu LJ, Sun YU, Maurya S, McGrosso D, Gonzalez DJ,. Caffrey CR, Debnath A. and Siqueira-Neto JL. A Broad Spectrum Antiparasitic Activity of Organotin (IV) Derivatives and its Untargeted Proteomic Profiling Using Leishmania donovani. Pathogens (accepted Nov 2022).

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67. Elsaid K, Merriman TR, Rossitto LA, Liu-Bryan R, Karsh J, Phipps-Green A, Jay GD, Elsayed S, Qadri M, Miner M, Cadzow M, Dambruoso TJ, Schmidt T, Dalbeth N, Chhana A, Höglund J, Ghassemian M, Campeau A, Maltez N, Karlsson NG, Gonzalez DJ, Terkeltaub R. Amplification of inflammation by lubricin deficiency implicated in incident, erosive gout independent of hyperuricemia via an experiment of nature. Arthritis & Rheumatology (accepted Nov 2022).

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66. Lorden G, Wozniak JM, Doré K,  Dozier L, Cates-Gatto C, Patrick G, Gonzalez DJ, Roberts A,  Tanzi R, and  Newton A. Enhanced Activity of Alzheimer Disease-associated Variant of Protein Kinase Cα Drives Cognitive Decline in a Mouse Model. Nature Communications (accepted Nov 2022).

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65. Gonzalez CG, Mills RH, Zhu Q, Sauceda C, Knight R, Dulai PS & Gonzalez DJ. Location-Specific Signatures of Crohn’s Disease at a Multi-omics Scale. Microbiome 2022 Aug 24;10(1):133.

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64. Russell BJ, Brown SD, Siguenza N, Mai I, Saran AR, Lingaraju A, Maissy E, Machado ACD, Pinto AFM, Sanchez C, Rossitto LA, Miyamoto Y, Richter RA, Ho SB, Eckmann L, Hasty J, Gonzalez DJ, Saghatelian A, Knight R, Zarrinpar A. Intestinal Transgene Delivery with Native E. coli Chassis Allows Persistent Physiological Changes. Cell.  2022 Aug 18;185(17):3263-3277.

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63. Gauglitz JM#, West KA#, Bittremieux W#, et al., Gonzalez DJ, Knight R*, Dorrestein PC*. Enhancing metabolomics annotations using metadata-based source annotation. Nature Biotechnology. (accepted 2022)

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62. Sakoulas G, McGrosso D, Gonzalez DJ, Dehner M, and Geriak M. Case Series of Intravenous Immunoglobulin (IVIG) Therapy In Severe COVID-19 Infection Complicating Pregnancy. American Journal of Case Reports (accepted 2022)

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61. Pilo CA, Baffi TR, Kornev AP, Kunkel MT, Malfavon M, Chen D, Rossitto LA, Chen D, Huang L, Longman C, Kannan N, Raskind W,  Gonzalez DJ, Taylor SS, Gorrie G, Newton AC. Protein Kinase Cγ Mutations Drive Spinocerebellar Ataxia Type 14 by Impairing Autoinhibition. Science Signaling. 2022 Sep 27;15(753):eabk1147. ***COVER ARTICLE

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60. Gonzalez CG, Mills RH, Kordahi MC, Carrillo-Terrazas M, Secaira-Morocho H, Widjaja CE, Tsai MS, Mittal Y, Yee BA, Vargas F, Weldon K, Gauglitz JM, Delaroque C, Sauceda C, Rossitto LA, Ackermann G, Humphrey G, Swafford AD, Siegel CA, Buckey Jr JC, Raffals LE, Sadler C, Lindholm P,Fisch KM, Valaseck M, Suriawinata A, Yeo GW, Ghosh P, Chang JT, Chu H, Dorrestein PC, Zhu Q, Chassaing B, Knight R, Gonzalez DJ, Dulai PS. Ulcerative Colitis Host-Microbiome Response to Hyperbaric Oxygen Therapy. Cellular and Molecular Gastroenterology and Hepatology (accepted 2022)

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59. Molinar-Inglis O, Wozniak JM, Grimsey N,  Orduña-Castillo L, Cheng N, Lin Y, Gonzalez Ramirez ML, Birch C , Lapek JD , Gonzalez DJ, Trejo J. Phosphoproteomic analysis of thrombin- and p38 MAPK-regulated signaling networks in endothelial cells. J Biol Chem. 2022 Mar 4;101801.

58. Oom AL, Stoneham CA, Lewinski MK, Richards A, Wozniak JM, Shams-Ud-Doha K, Gonzalez DJ, Krogan NJ, Guatelli J. Comparative Analysis of T Cell Spatial Proteomics and the Influence of HIV Expression. Mol Cell Proteomics. 2022 Jan 8:100194.

57. Mills RH, Dulai PS, Vázquez-Baeza Y, Sauceda C, Daniel N, Gerner RR, Batachari LE, Malfavon M, Zhu Q, Weldon K, Humphrey G, Carrillo-Terrazas M, Goldasich LD, Bryant M, Raffatellu M, Quinn RA, Gewirtz AT, Chassaing B, Chu H, Sandborn WJ, Dorrestein PC, Knight R*, Gonzalez DJ*. Multi-omics analyses of the Ulcerative Colitis gut microbiome link Bacteroides vulgatus proteases with disease severity. Nature Microbiology. 2022 Feb;7(2):262-276. *denotes co-corresponding authors

 

2021

56. Stoneham CA, Langer S, De Jesus PD, Deerinck T, Wozniak JM, Lapek JD, Pache L, Chanda SK, Gonzalez DJ, Ellisman M, Guatelli J. A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor. PLoS Pathog  2021 Nov 29;17(11):e1009409.

55. O’Neill AM, Worthing K, Kulkarni N, Li F, Nakatsuji T, McGrosso D, Mills RH, Cheng J, Hata T, Gonzalez DJ and Gallo RL. Antimicrobials from a feline skin commensal bacterium inhibit drug-resistant S. pseudintermedius skin colonization and infection. Elife 2021 Oct 19;10:e66793.

 

54. Wu ZY*, Campeau A*, Liu CH, Gonzalez DJ, Yamaguchi M, Kawabata S, Lu CH, Lai CY, Chiu HC, Chang YC. Unique virulence role of post-translocational chaperone PrsA in shaping Streptococcus pyogenes secretome.

Virulence 2021 Dec;12(1):2633-2647. *denotes co-first authors

53. Campeau A, Uchiyama S, Sanchez C, Sauceda C, Nizet V, Gonzalez DJ. The S protein of group B Streptococcus is a critical virulence determinant that impacts the cell surface virulome. Front Microbiol. 2021 Oct 14;12:729308.

52. Campeau A, Mills RH , Stevens T, Rossitto L, Meehan M, Dorrestein PC, Daly R, Nguyen TT, Gonzalez DJ*, Jeste DV*, Hook V*. Multi-omics of Human Plasma Reveals Molecular Features of Dysregulated Inflammation and Accelerated Aging in Schizophrenia. Mol Psychiatry. 2021 Nov 5. *denotes co-corresponding authors

 

51. Rada CC, Mejia-Pena H, Grimsey NJ, Cordova IC, Olson J, Wozniak J, Gonzalez DJ, Nizet V, and Trejo J. Resolution of GPCR-induced endothelial barrier permeability is mediated by heat shock protein 27. Science Signaling (accepted Aug 2021)

50. Wedegaertner H, Pan W, Gonzalez CC, Gonzalez DJ and Trejo J. The a-arrestin ARRDC3 is an Emerging Multifunctional Adaptor Protein in Cancer. Antioxid Redox Signal. 2022 Jan 4.

49.  Kaulich M, Link VM,  Lapek JD, Lee YJ, Glass CK, Gonzalez DJ, Dowdy SF. A Cdk4/6-Dependent phosphorylation gradient regulates the early to late G1 phase transition. Sci Rep 11, 14736 (2021).

48. Agelidis A, Suryawanshi RK, Patil CD, Campeau A, Gonzalez DJ, Shukla D. Dissociation of DNA damage sensing by endoglycosidase HPSE. iScience. 2021 Mar 19; 24(3): 102242.

47. Agelidis A, Turturice BA, Suryawanshi RK, Yadavalli T, Jaishankar D, Ames J, Hopkins J, Koujah L, Patil CD, Hadigal SR, Kyzar EJ, Campeau A, Wozniak JM, Gonzalez DJ, Vlodavsky I, Li JP, Perkins DL, Finn PW, Shukla D. Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival. JCI Insight. 2021 Apr 8; 6(7): e144255.

46.  Awdishu L, Le A, Amato J, Jani V, Bal S, Mills RH, Carrillo-Terrazas M, Gonzalez DJ, Tolwani A, Acharya A, Cerda J, Joy MS, Nicoletti P, Macedo E, Vaingankar S, Mehta R,  RamachandraRao SP. Urinary exosomes Identify Inflammatory Pathways in Vancomycin Associated Acute Kidney Injury. Int J Mol Sci. 2021 Mar; 22(6): 2784.

45.  Aubol BE, Wozniak JM, Fattet L, Gonzalez DJ, Adams JA. CLK1 Reorganizes the Splicing Factor U1-70K For Early Spliceosomal Protein Assembly. Proc Natl Acad Sci U S A. 2021 Apr 06; 118(14).

44.  Baffi TR, Lordén G, Wozniak JM, Feichtner A, Yeung W, Kornev AP, King CC, Del Rio JC, Limaye AJ, Bogomolovas J, Gould CM, Chen J,. Kennedy EJ, Kannan N, Gonzalez DJ, Stefan E, Taylor SS, Newton AC. mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR-interaction motif. Sci Signal. 2021 Apr 13; 14(678): eabe4509.

43. Takahashi M, Lio CW, Campeau A, Steger M, Ay F, Gonzalez DJ, Jain M, Sharma S. The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFNβ pathway. Nat Immunol. 2021 Apr 22(4):485-496.

Assistant Professor Publications 2015-2021

2020

42. Kaur H, Patra K, Kohli SK, Wozniak JM, Prieto JH, Yates III JR, Gonzalez DJ, Janse CJ and Vinetz JM. Plasmodium Ookinete Invasion Complex Heteromultimeric, Chitinase-containing Plasmodium falciparum and Plasmodium gallinaceum Ookinete-secreted Protein Complex Involved in Mosquito Midgut Invasion. Front Cell Infect Microbiol. (Accepted Dec 2020)

41. Vrbanac A, Patras KA, Jarmusch AK, Mills RH, Shing SR, Quinn RA, Vargas F, Gonzalez DJ, Dorrestein PC, Knight R, Nizet V. Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic. mSystems. 2020 Oct 06; 5(5).

40. Wozniak JM, Mills RH, Olson J, Caldera JR, Poore GD, Carrillo-Terrazas M, Tsai CM, Vargas F, Knight R, Dorrestein PC, Liu G, Nizet V, Sakoulas G, Rose W, Gonzalez DJ. Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Molecular Signatures. Cell. 2020 Sep 3;182(5):1311-1327. Commentaries: x-mol.com, genengnews.com, news-medical.net, health.ucsd.edu.

39. Ramirez-Sanchez I, Navarrete-Yañez V, Garate-Carrillo A, Loredo M, Lira-Romero E, Estrada-Mena J, Campeau A, Gonzalez DJ, Carrillo-Terrazas M, Moreno-Ulloa A, Ceballos G, Villarreal F. Development of muscle atrophy and loss of function in a Gulf-War illness model: underlying mechanisms.  Sci Rep . 2020 Sep 3;10(1):14526.

38. Campeau A, Mills RH, Blanchette M, Bajc K, Malfavon M, Munji RN, Deng L, Hancock B, Patras KA, Olson J, Nizet V, Daneman R, Doran K, Gonzalez DJ. Multidimensional Proteome Profiling of Blood-Brain Barrier Perturbation by Group B Streptococcus. mSystems. 2020 Aug 25;5(4):e00368-20.

37. Heckmann D, Campeau A, Lloyd CJ, Phaneuf  PV, Hefner Y, Terrazas M, Feist AM, Gonzalez DJ, Palsson B. Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers. Proc Natl Acad Sci U S A.  2020 Sep 15;117(37):23182-23190.

36. Chandrashekar DS, Golonka RM, Yeoh BS, Gonzalez DJ, Heikenwälder M, Gerwirtz AT, Varambally S, Vijay-Kumar M. Fermentable fiber-induced hepatocellular carcinoma in mice recapitulates gene signatures found in human liver cancer. PLoS One. 2020 Jun 19;15(6):e0234726.

35. Rojony R, Danelishvili L, Campeau A, Wozniak JM, Gonzalez DJ, Bermudez LE. Exposure of Mycobacterium abscessus to Environmental Stress and Clinically Used Antibiotics Reveals Common Proteome Response among Pathogenic Mycobacteria. Microorganisms. 2020 May; 8(5): 698.

34. Wozniak JM, Silva TA, Thomas D, Siqueira-Neto JL, McKerrow JH, Gonzalez DJ+, Calvet CM+. Molecular Dissection of Chagas Induced Cardiomyopathy Reveals Central Disease Associated and Druggable Signaling Pathways. PLoS Negl Trop Dis. 2020 May; 14(5). +denotes co-corresponding authors

33. Golonka RM, Yeoh XS, Li Y, Saha P, Abokor AA, Cheng X, Xiao X, Chandrashekar DS, Varambally S, Gonzalez DJ, Ross C, Kumar MV. Fermentable fibers induce rapid macro- and micronutrient depletion in Toll-like receptor 5-deficient mice. Am J Physiol Gastrointest Liver Physiol. 318: G955–G965, 2020.

32. Mills RH, Wozniak JM, Vrbanac A, Campeau A, Chassaing B, Gewirtz A, Knight R, Gonzalez DJ. Organ level protein networks as a reference for the host effects of the microbiome. Genome Res. 2020 Feb;30(2):276-286.

31. Lina Y, Wozniak JM, Grimseya NJ, Giradaa S, Patwardhana A, Molinar-Inglisa O, Smith TH, Lapek JD, Gonzalez DJ, Trejo J. Phospho-proteomic analysis of protease-activated receptor-1biasedsignaling reveals novel modulators of endothelial barrier function. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5039-5048.

30. O'Neill A, Nakatsuji T, Mills RH, Gonzalez DJ, Gallo R. Identification of a human skin commensal bacterium that selectively kills Cutibacterium acnes. Journal of Investigative Dermatology. 2020 Aug;140(8):1619-1628.
 
2019

29. Rojony R, Martin M, Campeau A, Wozniak JM, Gonzalez DJ, Jaiswal P, Danelishvili1 L and Bermudez LE. Quantitative analysis of Mycobacterium avium subsp. hominissuis proteome in response to antibiotics and during exposure to different environmental conditions. Clinical Proteomics volume 16, Article number: 39 (2019).

28. Wierzbicki IH, Campeau A, Dehaini D, Wei X, Ying M, Sands JS, Lamsa A, Pogliano J, Fang RH, LaRock CN, Zhang L, Gonzalez DJ. Group A Streptococcal S protein utilizes red blood cells as immune camouflage and is a critical determinant for adaptive immunity evasion. Cell Reports. 2019 Dec 3;29(10):2979-2989. Commentaries: Immunopaedia.org.za, phys.org, id-hub.com, smithsonianmag.com, drugtargetreview.com, eurekalert.org, sciencedaily.com.

27. Korandla DR, Wozniak JM, Campeau A, Gonzalez DJ, Wright ES. AssessORF: combining evolutionary conservation and proteomics to assess prokaryotic gene predictions. Bioinformatics. 2019 Sep 18. pii: btz714. doi: 10.1093/bioinformatics/btz714.

26. Gao NJ, Al-Bassam MM, Poudel S, Wozniak JM, Olson J, Gonzalez DJ, Zengler K, Nizet V, Valderrama JA. Functional and proteomic analysis of Streptococcus pyogenes virulence upon loss of its native Cas9 nuclease. Frontiers in Microbiology  2019 Aug 22;10:1967.

25. Tran HQ, RH Mills, Peters NV, Holder MK, de Vries GJ, Knight R, Chassaing B, Gonzalez DJ+, Gewirtz AT+. Associations of the Fecal Microbial Proteome Composition and Proneness to Diet-induced Obesity. Mol Cell Proteomics. 2019 Sep;18(9):1864-1879. + denotes co-corresponding authors [selected as cover article]

24. Wozniak JM and Gonzalez DJ. PhosPhinder: an R package for phospho-site localization and motif extraction from phospho-proteomic datasets. PeerJ.  2019 Jun 4;7:e7046.

23. Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak J, Barahona R, Kamei C, Houston J, Terrazas MC, Drummond I, Gonzalez DJ, Karl Willert, and David Traver. GFR is required for Wnt9a/Fzd9b signaling specificity in haematopoietic stem cells. Nature Cell Biology 2019 Jun;21(6):721-730.

22. Quinn RA, Adem S, Mills RH, Comstock W, DeRight Goldasich L, Humphrey G, Aksenov AA, Melnik AV, da Silva R, Ackermann G, Bandeira N, Gonzalez DJ, Conrad D, O'Donoghue AJ, Knight R, Dorrestein PC. Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome. Microbiome. 2019; 7(1):23.

21. Mills RH, Vázquez-Baeza Y, Zhu Q, Jiang L, Gaffney J, Humphrey G, Smarr L, Knight R+, Gonzalez DJ+. Evaluating Metagenomic Prediction of the Metaproteome in a 4.5-Year Study of a Patient with Crohn’s Disease. mSystems. 2019; 4(1). + denotes co-corresponding authors

20. Lapek JD, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ+ and O'Donoghue AJ+. Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry. Molecular Cellular Proteomics. 2019;7(9). + denotes co-corresponding authors

19. Breuer M, Earnest TM, Merryman C, Wise KS, Sun L, Lynott MR, Hutchison III CA, Smith HO, Lapek JD, Gonzalez DJ, Lagard VC, Haas D, Hanson AD, Labhsetwar P, Glass JI, and Luthey-Schulten Z. Essential Metabolism for a Minimal Cell. eLife. 2019;8:e36842 doi: 10.7554/eLife.36842.
 
2018

18. Singh V, Yeoh BS, Chassaing B, Xiao X, Saha P, Olvera RA, Lapek JD, Zhang L, Wang W, Hao S, Flythe MD, Gonzalez DJ, Cani PD, Conejo-Garcia JR, Xiong N, Kennett MJ, Joe B, Patterson AD, Gewirtz AT, Vijay-Kumar M. Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer. Cell. 2018 Oct 18;175(3):679-694.

17. Al-Bassam M, Kim J, Zaramela L, Kellman B, Zuniga C, Wozniak JM, Gonzalez DJ, Zengler K. Optimization of Carbon and Energy Utilization Through Differential Translational Efficiency. Nature communications. 2018 Oct 26;9(1):4474.

16. Solomon T, Lapek JD, Jr, Jensen SB, Greenwald WW, Hindberg K, Matsui H, Latysheva N, Braekken SK, Gonzalez DJ, Frazer KA, Smith EN, Hansen JB. Identification of Common and Rare Genetic Variation Associated with Plasma Protein Levels Using Whole-Exome Sequencing and Mass Spectrometry. Circulation:  Genomic Precision Medicine. 2018 Dec;11(12):e002170.

15.  Jensen SB, Hindberg K, Solomon T, Smith EN, Lapek JD, Gonzalez DJ, Latysheva N, Frazer KA, Brækkan SK, Hansen JB. Discovery of novel plasma biomarkers for future incident venous thromboembolism by un targeted synchronous precursor selection mass spectrometry proteomics. Journal of thrombosis and haemostasis. 2018 Sep;16(9):1763-1774.

14. Grimsey NJ, Narala R, Rada CC, Mehta S, Stephens BS, Kufareva I, Lapek JD, Gonzalez DJ, Handel TM, Zhang J and Trejo J. A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling. Cell Reports. 2018 Sep 18;24(12):3312-3323.

13. Patras KA, Derieux J, Al-Bassam MM, Adiletta N, Vrbanac A, Lapek JD, Zengler K, Gonzalez DJ, Nizet V. Group B Streptococcus biofilm regulatory protein A contributes to bacterial physiology and innate immune resistance. Journal of Infectious Diseases. 2018 Oct 5;218(10):1641-1652.

12. Daniel McDonald, Embriette R Hyde, Justine W Debelius, James T Morton, Antonio Gonzalez, Gail Ackermann, Alexander A Aksenov, Bahar Behsaz, Caitriona Brennan, Yingfeng Chen, Lindsay DeRight Goldasicha, Pieter C Dorrestein, Robert R Dunn, Ashkaan K Fahimipourg, James Gaffney, Jack A Gilbert, Grant Gogul, Jessica L Green, Philip Hugenholtz, Greg Humphrey, Curtis Huttenhower, Matthew A Jackson, Stefan Janssen, Dilip V Jeste, Lingjing Jiang, Scott T Kelley, Dan Knights, Tomasz Kosciolek, Joshua Ladau, Jeff Leach, Clarisse Marotz, Dmitry Meleshko, Alexey V Melnik, Jessica L Metcalf, Hosein Mohimani, Emmanual Montassier, Jose Navas-Molina, Tanya T Nguyen, Shyamal Peddada, Pavel Pevzner, Katherine S Pollard, Gholamali Rahnavard, Adam Robbins-Pianka, Naseer Sangwan, Joshua Shorenstein, Larry Smarr, Se Jin Song, Timothy Spector, Austin D Swafford, Varykina G Thackray, Luke R Thompson, Anupriya Tripathi, Yoshiki Vazquez-Baeza, Alison Vrbanac, Paul Wischmeyer, Elaine Wolfe, Qiyun Zhu, American Gut Consortium, Rob Knight. American Gut: an Open Platform for Citizen-Science Microbiome Research. mSystems. 2018 May 15;3(3).

11. Wang H, Lapek JD, Fujimura K, Strnadel J, Liu B, Gonzalez DJ, Zhang W, Watson F, Yu V, Liu C, Muccilo CM, Miller YY, Elliott KC, Cheresh DA, Klemke RL. “Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription”. Cell Discovery.  2018 May 29;4:26.

10. Lapek JD*, Mills RH*, Wozniak JM, Campeau A, Fang R, Wei X, van de Groep K, van Sorge NM, Perez-Lopez A, Raffatellu M, Knight R, Zhang L, Gonzalez DJ. Defining Host Responses During Systemic Bacterial Infection Through Construction of a Murine Organ Proteome Atlas. Cell Systems. May 23;6(5):579-592. * Preview written on article: Cell Systems, 2018 May 23;6(5):536-538.

9.  Perera R, Lapek JD, Newton G, Gonzalez DJ, Pogliano K. Identification of the S-transferase like superfamily bacillithiol transferases encoded by Bacillus subtilis. PLoS One. 2018 Feb 16;13(2):e0192977.

8. Askarian F, Lapek JD, Dongre M, Tsai C, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh PJ, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M. Staphylococcus aureus Membrane-derived Vesicles Promote Bacterial Virulence and Confer a protective immunity in Murine Infection models. Frontiers in Microbiology  2018 Feb 20;9:262.

7.  Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lecuyer E, Yeo G. Context-dependent and disease-specific diversity in stress granules from pre-existing protein interactions. Cell. 2018 Jan 25;172(3):590-604.
 
2017

6.  Lapek JD Jr, Fang RH, Wei X, Li P, Wang B, Zhang L, Gonzalez DJ. Biomimetic Virulomics for Capture and Identification of Cell-Type Specific Effector Proteins. ACS Nano. 2017 Sep 20. * Perspective written on article: ACS Nano, 2017, 11 (12), pp 11768–11772.

5.  Pollak AJ, Haghighi K, Kunduri S, Arvanitis DA, Bidwell PA, Liu GS, Singh VP, Gonzalez DJ, Sanoudou D, Wiley SE, Dixon JE, Kranias EG. Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9098-9103.

4.  Formentini L, Ryan A, Galvez-Santisteban M, Carter L, Lapek J, Gonzalez DJ, Villarreal Ciaraldi TP, Cuezva JM, Henry RR. Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to insulin resistance in obesity and type 2 diabetes. Diabetologia. 2017 Oct;60(10):2052-2065.

3. Lapek JD Jr, Lewinski MK, Wozniak JM, Guatelli J, Gonzalez DJ. Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Protein Vpr. Mol Cell Proteomics. 2017 Aug;16(8):1447-1461.
 
2016

2.  Wang et al., Gonzalez DJ, Bandeira N. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 2016 Aug 9;34(8):828-37.
 
2015

1.  Corriden R, Hollands A, Olson J, Derieux J, Lopez J, Chang JT, Gonzalez DJ, Nizet V. Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide. Nature Communication. 2015 Oct 13; 6:836.